It was recently reported in a survey of European centers that 31.8% of patients with severe, isolated, symptomatic aortic stenosis were not offered surgical therapy due to risk level, comorbidities, or patient refusal.5 A large academic medical center in the United States reported a review of echocardiographic results from their institution that showed only 453 out of 740 patients (61%) with severe aortic stenosis — defined as aortic valve area (AVA) of 0.8 cm2 or less — received surgery.6 In the United States, it is estimated that about 749,000 patients have aortic stenosis and, of these, 125,000 have severe stenosis. This can be compared to the estimated number of AVR operations done in the United States annually of 70,000. It is clear that there is a substantial population with severe, life-threatening aortic stenosis that is underserved. This has led to the search for less morbid treatment options for aortic stenosis.

" /> It was recently reported in a survey of European centers that 31.8% of patients with severe, isolated, symptomatic aortic stenosis were not offered surgical therapy due to risk level, comorbidities, or patient refusal.5 A large academic medical center in the United States reported a review of echocardiographic results from their institution that showed only 453 out of 740 patients (61%) with severe aortic stenosis — defined as aortic valve area (AVA) of 0.8 cm2 or less — received surgery.6 In the United States, it is estimated that about 749,000 patients have aortic stenosis and, of these, 125,000 have severe stenosis. This can be compared to the estimated number of AVR operations done in the United States annually of 70,000. It is clear that there is a substantial population with severe, life-threatening aortic stenosis that is underserved. This has led to the search for less morbid treatment options for aortic stenosis.

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Methodist Journal

FEATURED GUEST EDITOR

ISSUE INTRO

The Scourge of Cardiogenic Shock

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RECOGNITIONS

Arvind Bhimaraj, MD, MPH, Guides Issue on Cardiogenic Shock

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REVIEW ARTICLES See More

Cardiovascular Implications of COVID-19 Infections

Pathophysiology and Advanced Hemodynamic Assessment of Cardiogenic Shock

Cardiogenic Shock in the Setting of Acute Myocardial Infarction

Cardiogenic Shock in Patients with Advanced Chronic Heart Failure

Acute Mechanical Circulatory Support for Cardiogenic Shock

Management of Cardiogenic Shock in a Cardiac Intensive Care Unit

Physiological Concepts of Cardiogenic Shock Using Pressure-Volume Loop Simulations: A Case-Based Review

Systems of Care in Cardiogenic Shock

CASE REPORTS See More

COVID-19: A Potential Risk Factor for Acute Pulmonary Embolism

Repair of Extent III Thoracoabdominal Aneurysm in the Presence of Aortoiliac Occlusion

Williams-Beuren Syndrome: The Role of Cardiac CT in Diagnosis

A Rare Case of Pancreatitis-Induced Thrombosis of the Aorta and Superior Mesenteric Artery

MUSEUM OF HMH MULTIMODALITY IMAGING CENTER See More

A T2-Weighty Discovery: Aortitis on Cardiac MRI with Histopathologic Correlation

CLINICAL PERSPECTIVES See More

POINTS TO REMEMBER

Acute Kidney Injury in Cardiogenic Shock

EXCERPTA

Cardio-Oncology, Then and Now: An Interview with Barry Trachtenberg

POINTS TO REMEMBER

Onconephrology: An Evolving Field

POINTS TO REMEMBER

Herbal Nephropathy

EDITORIALS

Letter to the Editor in Response to “Cardiac Autonomic Neuropathy in Diabetes Mellitus”