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Use of Stem Cells in Heart Failure Treatment: Where We Stand and Where We Are Going

Authors:

Luis A. Sánchez ,

Cátedra de Cardiología y Medicina Vascular, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, MX
About Luis A.
M.D.
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Carlos Enrique Guerrero-Beltrán,

Cátedra de Cardiología y Medicina Vascular, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, MX
About Carlos Enrique
M.D.
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Andrea M. Cordero-Reyes,

Cátedra de Cardiología y Medicina Vascular, Escuela de Medicina, Tecnológico de Monterrey, Monterrey, MX; Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US
About Andrea M.
M.D.
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Gerardo García-Rivas,

Cátedra de Cardiología y Medicina Vascular, Escuela de Medicina, Tecnológico de Monterrey, Monterrey; Instituto de Cardiología y Medicina Vascular, Tec Salud, San Pedro Garza García, MX
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Ph.D.
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Guillermo Torre-Amione

Cátedra de Cardiología y Medicina Vascular, Escuela de Medicina, Tecnológico de Monterrey, Monterrey; Instituto de Cardiología y Medicina Vascular, Tec Salud, San Pedro Garza García, MX; Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US
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M.D., Ph.D.
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Abstract

End-stage heart failure is the final common pathway of an irreversible process associated with loss of myocardial cells. In this process, the capacity for renewal and repair of myocardial tissue is inadequate and ultimately leads to ventricular remodeling. Novel therapeutic strategies have been developed to prevent it, one being cell therapy, which has emerged as a potential approach to directly repopulate and repair the damaged heart. Here, we review the use of regenerative cell therapy for different cardiac diseases and discuss the positive effect of cell therapy mediated by paracrine factors instead of turning directly into cardiomyocytes.

How to Cite: 1. Sánchez LA, Guerrero-Beltrán CE, Cordero-Reyes AM, García-Rivas G, Torre-Amione G. Use of Stem Cells in Heart Failure Treatment: Where We Stand and Where We Are Going. Methodist DeBakey Cardiovascular Journal. 2013;9(4):195-200. DOI: http://doi.org/10.14797/mdcj-9-4-195
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Published on 01 Oct 2013.
Peer Reviewed

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