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Endovascular Techniques in Limb Salvage: Cutting, Cryo, Brachy, and Drug-Eluting Balloons

Authors:

Mark G. Davies ,

Methodist DeBakey Heart & Vascular Center, The Methodist Hospital, Houston, Texas, US
About Mark G.
M.D., Ph.D., M.B.A.
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Javier E. Anaya-Ayala

Methodist DeBakey Heart & Vascular Center, The Methodist Hospital, Houston, Texas, US
About Javier E.
M.D.
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Abstract

The complex pathophysiology response to injury of the lower-extremity arteries has prompted the development of several unique balloon technologies to overcome initial technical failures and short-term intimal hyperplasia. Cryoplasty alters the cellular and mechanical properties of the vessel wall during angioplasty. Cutting balloons incise the wall, preventing elastic recoil and allowing expansion of the lumen at a lower pressure, thus limiting barotrauma. Drug-eluting balloons actively transfer inhibitory compounds to the wall during the initial therapy, while brachytherapy balloons allow for localized delivery of radiation to inhibit the proliferative response seen after angioplasty. These platforms provide unique means to enhance immediate and short-term results and also reduce stent usage in the lower extremity.

How to Cite: 1. Davies MG, Anaya-Ayala JE. Endovascular Techniques in Limb Salvage: Cutting, Cryo, Brachy, and Drug-Eluting Balloons. Methodist DeBakey Cardiovascular Journal. 2013;9(2):69-72. DOI: http://doi.org/10.14797/mdcj-9-2-69
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Published on 01 Apr 2013.
Peer Reviewed

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