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Fatty Liver: A Link to Cardiovascular Disease – Its Natural History, Pathogenesis, and Treatment

Authors:

Howard P. Monsour, Jr. ,

The Methodist Hospital, Houston, Texas, US
About Howard P.
M.D.
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Catherine T. Frenette,

The Methodist Hospital, Houston, Texas; Weill Cornell Medical College, New York, New York, US
About Catherine T.
M.D.
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Kathleen Wyne

The Methodist Hospital, Houston, Texas; Weill Cornell Medical College, New York, New York, US
About Kathleen
M.D., Ph.D.
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Abstract

Nonalcoholic fatty liver disease (NAFLD) has become the most prevalent liver disease in western society and is increasing in parallel with the worldwide epidemic of obesity. It exists in a simple form, steatosis, or a more complex and more dangerous form, steatohepatitis, and it is often but not always associated with the metabolic syndrome. NAFLD can progress to cirrhosis and hepatocellular carcinoma. It is responsible for the majority of cryptogenic cirrhosis cases. Increasingly, NAFLD and its more sinister form, steatohepatitis, have been linked to the increased incidence of cardiovascular disease (CVD) worldwide, independent of the metabolic syndrome. Death from CVD surpasses death from liver complications, but that is beginning to change as people are living longer with CVD. In this article, we will review nonalcoholic fatty liver disease and its epidemiology, prevalence, pathology, and link to CVD.

How to Cite: 1. Monsour, Jr. HP, Frenette CT, Wyne K. Fatty Liver: A Link to Cardiovascular Disease – Its Natural History, Pathogenesis, and Treatment. Methodist DeBakey Cardiovascular Journal. 2012;8(3):21-25. DOI: http://doi.org/10.14797/mdcj-8-3-21
Published on 01 Jul 2012.
Peer Reviewed

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