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Orthotopic Heart Transplant Facilitated Autologous Hematopoietic Stem Cell Transplantation in Light-Chain Amyloidosis

Author:

Rammurti T. Kamble

Baylor College of Medicine and The Methodist Hospital, Houston, Texas, US
About Rammurti T.
M.D.
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Abstract

Initial manifestations of light-chain amyloidosis (AL) are variable and often result in missed or delayed diagnosis. Survival in AL patients depends mainly on the severity of cardiac involvement. Dominant stage-III cardiac involvement due to primary systemic amyloidosis precludes effective AL treatment and is associated with an average survival of only 3–4 months. The following paper discusses the benefits of orthotopic heart transplantation and autologous hematopoietic stem cell transplantation to improve survival in patients with progressive cardiac AL.

How to Cite: 1. Kamble RT. Orthotopic Heart Transplant Facilitated Autologous Hematopoietic Stem Cell Transplantation in Light-Chain Amyloidosis. Methodist DeBakey Cardiovascular Journal. 2012;8(3):17-18. DOI: http://doi.org/10.14797/mdcj-8-3-17
Published on 01 Jul 2012.
Peer Reviewed

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