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High-Resolution CT Vascular Imaging Using Blood Pool Contrast Agents

Authors:

Ananth V. Annapragada ,

The Singleton Department of Pediatric Radiology, Texas Children’s Hospital, Houston, Texas, US
About Ananth V.
Ph.D.
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Eric Hoffman,

Department of Radiology, The University of Iowa Carver College of Medicine, Iowa City, Iowa, US
About Eric
Ph.D.
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Abhay Divekar,

Department of Pediatric Cardiology, The University of Iowa Carver College of Medicine, Iowa City, Iowa, US
About Abhay
M.B.B.S., M.D.
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Efstathios Karathanasis,

Case Center for Imaging Research, Case Western Reserve University, Cleveland, Ohio, US
About Efstathios
Ph.D.
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Ketan B. Ghaghada

The Singleton Department of Pediatric Radiology, Texas Children’s Hospital, Houston, Texas, US
About Ketan B.
Ph.D.
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Abstract

Introduction

While the evolution of computed tomography imaging in the last 2 decades has been driven almost exclusively by improvements in the instrumentation and processing algorithms, there have been comparatively modest advances in contrast agent technology. A notable change in the last decade has been the development of blood pool contrast agents based on nanoparticle technology. While not yet ready for clinical use, the stable and uniform opacification provided by these agents in normal vasculature and controlled extravasation in compromised vasculature enables novel techniques for imaging and diagnosis of pathologies. This manuscript presents preclinical examples demonstrating cardiovascular pathologies and tumor characterization by high-resolution computed tomography imaging.

How to Cite: 1. Annapragada AV, Hoffman E, Divekar A, Karathanasis E, Ghaghada KB. High-Resolution CT Vascular Imaging Using Blood Pool Contrast Agents. Methodist DeBakey Cardiovascular Journal. 2012;8(1):18-22. DOI: http://doi.org/10.14797/mdcj-8-1-18
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Published on 01 Jan 2012.
Peer Reviewed

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