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Case Reports

Cardiac Tumor Resection and Repair with Porcine Xenograft

Authors:

Walid K. Abu Saleh ,

Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US
About Walid K.
M.D.
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Odeaa Al Jabbari,

Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US
About Odeaa
M.D.
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Basel Ramlawi,

Valley Health System, Winchester, Virginia, US
About Basel
M.D.
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Brian A. Bruckner,

J.C. Walter Jr. Transplant Center, Houston Methodist Hospital, Houston, Texas, US
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M.D.
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Matthias Loebe,

University of Miami Leonard M. Miller School of Medicine, Miami, Florida, US
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M.D., Ph.D.
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Michael J. Reardon

Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US
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M.D.
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Abstract

Primary cardiac sarcomas are rare and carry a grave prognosis. Improved survival requires a complete margin negative resection of the tumor. These surgical resections are often large and complex, requiring extensive reconstructive procedures. The appropriate material for cardiac reconstruction is not known. We have used glutaraldehyde-fixed bovine pericardium in our early series but have recently employed the MatriStem® Surgical Matrix PSMX membrane (ACell®, Inc.; Columbia, MD), a unique proprietary urinary bladder matrix derived from porcine urinary bladder with the potential for viability and tissue ingrowth. In our study of six patients at this institution, all six underwent successful surgical resection and repair with the MatriStem acellular porcine urinary bladder membrane (ACell). The postoperative course was uncomplicated in all patients, and they are still alive at this time. An aggressive surgical approach to cardiac tumors can possibly lead to complete resection but often requires reconstruction of the cardiac tissue with a membrane. We were able to achieve acceptable results in our cardiac reconstruction by using the ACell extracellular matrix to reconstruct the defect following tumor resection. Longer-term follow-up in these patients, including imaging studies, will be necessary to demonstrate the durability and integrity of the reconstruction.

How to Cite: 1. Abu Saleh WK, Al Jabbari O, Ramlawi B, Bruckner BA, Loebe M, Reardon MJ. Cardiac Tumor Resection and Repair with Porcine Xenograft. Methodist DeBakey Cardiovascular Journal. 2016;12(2):116-118. DOI: http://doi.org/10.14797/mdcj-12-2-116
Published on 01 Apr 2016.
Peer Reviewed

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