Start Submission Become a Reviewer

Reading: Physiological Impact of Continuous Flow on End-Organ Function: Clinical Implications in the ...

Download

A- A+
Alt. Display

Review Articles

Physiological Impact of Continuous Flow on End-Organ Function: Clinical Implications in the Current Era of Left Ventricular Assist Devices

Authors:

Arvind Bhimaraj ,

Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US
About Arvind
M.D., M.P.H.
X close

Cesar Uribe,

Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US
About Cesar
M.D.
X close

Erick E. Suarez

Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US
About Erick E.
M.D.
X close

Abstract

The clinical era of continuous-flow left ventricular assist devices has debunked many myths about the dire need of a pulse for human existence. While this therapy has been documented to provide a clear survival benefit in end-stage heart failure patients, we are now faced with certain morbidity challenges that as of yet have no easy mechanistic physiological explanation. The effect of physiological changes on end-organ function in patients supported by continuous-flow ventricular assist devices may offer insight into some of these morbidities. We therefore present a review of current evidence documenting the impact of continuous flow on end-organ function.

How to Cite: 1. Bhimaraj A, Uribe C, Suarez EE. Physiological Impact of Continuous Flow on End-Organ Function: Clinical Implications in the Current Era of Left Ventricular Assist Devices. Methodist DeBakey Cardiovascular Journal. 2015;11(1):12-17. DOI: http://doi.org/10.14797/mdcj-11-1-12
Published on 01 Jan 2015.
Peer Reviewed

Downloads

  • PDF (EN)