Review Articles
Physiological Impact of Continuous Flow on End-Organ Function: Clinical Implications in the Current Era of Left Ventricular Assist Devices
Authors:
Arvind Bhimaraj ,
Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US
About Arvind
M.D., M.P.H.
Cesar Uribe,
Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US
About Cesar
M.D.
Erick E. Suarez
Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US
About Erick E.
M.D.
Abstract
The clinical era of continuous-flow left ventricular assist devices has debunked many myths about the dire need of a pulse for human existence. While this therapy has been documented to provide a clear survival benefit in end-stage heart failure patients, we are now faced with certain morbidity challenges that as of yet have no easy mechanistic physiological explanation. The effect of physiological changes on end-organ function in patients supported by continuous-flow ventricular assist devices may offer insight into some of these morbidities. We therefore present a review of current evidence documenting the impact of continuous flow on end-organ function.
How to Cite:
1. Bhimaraj A, Uribe C, Suarez EE. Physiological Impact of Continuous Flow on End-Organ Function: Clinical Implications in the Current Era of Left Ventricular Assist Devices. Methodist DeBakey Cardiovascular Journal. 2015;11(1):12-17. DOI: http://doi.org/10.14797/mdcj-11-1-12
Published on
01 Jan 2015.
Peer Reviewed
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