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Review of Recent Results using Computational Fluid Dynamics Simulations in Patients Receiving Mechanical Assist Devices for End-Stage Heart Failure

Authors:

Mina Berty Farag ,

University Hospital of Heidelberg, Heidelberg, DE
About Mina Berty
M.D.
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Christof Karmonik,

Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, US
About Christof
Ph.D.
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Fabian Rengier,

University Hospital of Heidelberg, Heidelberg, DE
About Fabian
M.D.
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Matthias Loebe,

Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas, US
About Matthias
M.D., Ph.D.
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Matthias Karck,

University Hospital of Heidelberg, Heidelberg, DE
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M.D.
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Hendrik von Tengg-Kobligk,

Institute for Diagnostic, Interventional and Pediatric Radiology, Inselspital Bern, Bern, CH
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M.D.
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Arjang Ruhparwar,

University Hospital of Heidelberg, Heidelberg, DE
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M.D., Ph.D.
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Sasan Partovi

University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, US
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M.D.
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Abstract

Many end-stage heart failure patients are not eligible to undergo heart transplantation due to organ shortage, and even those under consideration for transplantation might suffer long waiting periods. A better understanding of the hemodynamic impact of left ventricular assist devices (LVAD) on the cardiovascular system is therefore of great interest. Computational fluid dynamics (CFD) simulations give the opportunity to study the hemodynamics in this patient population using clinical imaging data such as computed tomographic angiography. This article reviews a recent study series involving patients with pulsatile and constant-flow LVAD devices in which CFD simulations were used to qualitatively and quantitatively assess blood flow dynamics in the thoracic aorta, demonstrating its potential to enhance the information available from medical imaging.

How to Cite: 1. Farag MB, Karmonik C, Rengier F, et al.. Review of Recent Results using Computational Fluid Dynamics Simulations in Patients Receiving Mechanical Assist Devices for End-Stage Heart Failure. Methodist DeBakey Cardiovascular Journal. 2014;10(3):185-189. DOI: http://doi.org/10.14797/mdcj-10-3-185
Published on 01 Jul 2014.
Peer Reviewed

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