Intracardiac Ultrasound-Guided Approaches for Managing Heart Rhythm Disorders
- Dirar S. KhouryEmail Dirar S. Khoury
Heart rhythm disorders (atrial and ventricular arrhythmias) result in significant morbidity and mortality. Atrial fibrillation is the most common cardiac arrhythmia, affecting more than two million Americans, responsible for one-third of all strokes in patients over 65 years of age, and costing $9 billion annually to manage.1 Another 300,000 Americans die of sudden cardiac death each year, mainly due to ventricular tachyarrhythmias that cause intractable, extremely rapid heartbeats.2
Since current pharmacological therapy for managing cardiac arrhythmias is often ineffective and can even be proarrhythmic, treatment has emphasized non-pharmacological therapies such as ablation, pacing and defibrillation. Effectively managing complex cardiac arrhythmias during electrophysiology studies hinges on several factors including: 1) developing catheter mapping techniques to identify causes and details of arrhythmias; 2) integrating anatomical imaging methods to connect the arrhythmias with underlying cardiac structure; 3) targeting non-pharmacological therapies to abolish arrhythmias; and 4} advancing diagnostic methods to elucidate the effects of therapy. This report is a brief review of recent translational research conducted in collaboration with scientists at Methodist DeBakey Heart Center and Baylor College of Medicine to address some of these issues.
- Published on 1 Jan 2005
- Peer Reviewed