Welcome to the latest issue of the Methodist DeBakey Cardiovascular Journal. Guest editor Hassan Ibrahim, MD, guided this overview of The Kidney and The Heart, exploring recent developments in the interaction between heart failure and kidney function. I appreciate his expertise and insights as well as those of the authors who contributed to this issue.

The review articles included here reflect our current understanding of the interdependency of heart and kidney function, the maladaptive roles of regulatory systems, and therapies that are demonstrating success in helping patients regardless of left ventricular function. A few highlights include the often-ignored impact of central venous congestion, the expanding need and indications for combined heart-kidney transplantation, the role of left ventricular assist devices, and the challenges of amyloidosis in the heart and kidney.

We also examine current guidelines for managing blood pressure in kidney transplant recipients, screening for cardiovascular disease in transplant candidates, recommendations for SGLT-2 inhibitors, and other possibilities for prevention. In the coming weeks, we’ll be sharing video highlights from conversations with our authors about challenges, therapies, and prevention for combined heart and kidney disease.

We invite you to share your clinical experiences by submitting case reports and multimodality imaging manuscripts at the submission link on our website. Our goal is to continually publish unusual, visually interesting, and informative cases in our online Case Reports Issue, which is peer reviewed and indexed in PubMed. You can read our year-round repository of case reports, interactive CME cases, and other articles with CME credit available in the journal’s Case Reports Collection.

As always, I appreciate your ongoing interest and welcome your feedback.

Miguel A. Quiñones, MD, MACC, FASE

Editor-in-Chief

Methodist DeBakey Cardiovascular Journal

Winters Family Distinguished Centennial Chair

in Cardiovascular Education, Houston Methodist DeBakey Heart & Vascular Center