Case Reports

Olmesartan-Induced Enteropathy



Olmesartan-induced enteropathy mimics celiac disease clinically and pathologically. As in celiac disease, the pathologic findings are villous atrophy and increased intraepithelial lymphocytes. Clinical presentation of olmesartan-induced enteropathy includes diarrhea, weight loss, and nausea. In contrast to celiac disease, tissue transglutaminase is not elevated and there is no response to a gluten-free diet. Including this entity in the differential diagnosis of sprue-like enteropathy is critical for its early diagnosis since replacing olmesartan with an alternative antihypertensive drug can simplify the diagnostic workup and provide both clinical and histologic improvement.


olmesartan-induced enteropathyceliac diseasediarrhea
  • Year: 2016
  • Volume: 12 Issue: 4
  • Page/Article: 230-232
  • DOI: 10.14797/mdcj-12-4-230
  • Published on 1 Oct 2016
  • Peer Reviewed