Abudiab MM, McKay J, Deavers M, Zoghbi WA, Chang SM. Pannus of Mitral Valve Prosthesis Causing Left Ventricular Outflow Tract Obstruction. Methodist DeBakey Cardiovasc  J. 2016;12(3):183." /> Abudiab MM, McKay J, Deavers M, Zoghbi WA, Chang SM. Pannus of Mitral Valve Prosthesis Causing Left Ventricular Outflow Tract Obstruction. Methodist DeBakey Cardiovasc  J. 2016;12(3):183."> Article Full Text – Methodist Journal
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Vol 12, Issue 3 (2016)

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MUSEUM OF HMH MULTIMODALITY IMAGING CENTER

Pannus of Mitral Valve Prosthesis Causing Left Ventricular Outflow Tract Obstruction

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Article Citation:

Abudiab MM, McKay J, Deavers M, Zoghbi WA, Chang SM. Pannus of Mitral Valve Prosthesis Causing Left Ventricular Outflow Tract Obstruction. Methodist DeBakey Cardiovasc  J. 2016;12(3):183.

doi: https://doi.org/10.14797/mdcj-12-3-183

Keywords
mitral valve replacement , stenosis , pannus , cardiovascular imaging

 

A 54-year-old female with mitral valve replacement presented to the Houston Methodist Hospital with chest pain and dyspnea. (A) Transthoracic echocardiography (TTE) demonstrated marked left ventricular outflow tract (LVOT) narrowing and a frozen aortic valve (AV) cusp (Video 1). (B) Spectral Doppler by TTE across the AV revealed high velocity with rounded contour. (C) Cardiac computed tomography (CT) confirmed suspicion that these findings were referable to extensive pannus formation involving the bioprosthetic mitral valve (Video 2). (D) Following surgical resection, the LVOT appeared normal on TTE. (E) Postoperative cardiac CT also showed return of normal AV leaflet excursion. (F) Pathology of the resected tissue was consistent with pannus, evidenced by fibrous tissue with hypocellular proliferation of bland spindle cells, abundant collagen, and scattered capillaries. TTE also revealed mild stenosis of the mitral prosthesis, with a mean diastolic gradient of 6 mm Hg.

While pannus can develop on both bioprosthetic and mechanical valves in the mitral position,1 extension into either adjoining cavity is unusual, typically involves only the left atrium, and is more typical of thrombosis.2 This is an interesting presentation since LVOT obstruction due to pannus of a mitral prosthesis is rarely seen.


Video 1: TTE shows LVOT narrowing and frozen AV cusp


Video 2: CT demonstrates pannus of bioprosthetic mitral valve

References
1. Pibarot P Dumesnil JG. Prosthetic heart valves: selection of the optimal prosthesis and long-term management. Circulation. 2009 Feb 24; 119( 7): 103448.
2. Barbetseas J , Nagueh SF , Pitsavos C , Toutouzas PK , Quinones MA , Zoghbi WA. Differentiating thrombus from pannus formation in obstructed mechanical prosthetic valves: an evaluation of clinical, transthoracic and transesophageal echocardiographic parameters. J Am Coll Cardiol. 1998 Nov; 32( 5): 14107.

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