Methodist Journal



The Scourge of Cardiogenic Shock

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Arvind Bhimaraj, MD, MPH, Guides Issue on Cardiogenic Shock

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Pathophysiology and Advanced Hemodynamic Assessment of Cardiogenic Shock

Cardiogenic Shock in the Setting of Acute Myocardial Infarction

Cardiogenic Shock in Patients with Advanced Chronic Heart Failure

Acute Mechanical Circulatory Support for Cardiogenic Shock

Management of Cardiogenic Shock in a Cardiac Intensive Care Unit

Physiological Concepts of Cardiogenic Shock Using Pressure-Volume Loop Simulations: A Case-Based Review

Systems of Care in Cardiogenic Shock

Cardiogenic Shock in Perioperative and Intraoperative Settings: A Team Approach


Repair of Extent III Thoracoabdominal Aneurysm in the Presence of Aortoiliac Occlusion

Williams-Beuren Syndrome: The Role of Cardiac CT in Diagnosis

A Rare Case of Pancreatitis-Induced Thrombosis of the Aorta and Superior Mesenteric Artery

Anomalous Origin of the Right Coronary Artery from the Left Main Coronary Artery in the Setting of Critical Bicuspid Aortic Valve Stenosis


A T2-Weighty Discovery: Aortitis on Cardiac MRI with Histopathologic Correlation



Acute Kidney Injury in Cardiogenic Shock


Cardio-Oncology, Then and Now: An Interview with Barry Trachtenberg


Onconephrology: An Evolving Field


Herbal Nephropathy


Letter to the Editor in Response to “Cardiac Autonomic Neuropathy in Diabetes Mellitus”

Vol 12, Issue 3 (2016)

Article Full Text


Position-Dependent Ventricular Tachycardia Related to Peripherally Inserted Central Venous Catheter

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Article Citation:

Alvarez P, Schurmann P, Smith M, Valderrábano M, Lin CH. Position-Dependent Ventricular Tachycardia Related to Peripherally Inserted Central Venous Catheter. Methodist DeBakey Cardiovasc J. 2016;12(3):177-178.



We report a case of a 51-year-old male who developed frequent nonsustained episodes of monomorphic ventricular tachycardia after being diagnosed with bioprosthetic aortic valve endocarditis and treated with intravenous antibiotics. A peripherally inserted central venous catheter (PICC) had been placed without complication less than 24 hours prior to the episodes. Ventricular tachycardia (VT) occurred during the night, while sleeping, when he assumed a right lateral decubitus position with abduction of the right arm and placement of the forearm under his head. VT occurred repeatedly when such position was assumed again upon request, and it would terminate immediately when sitting upright. The PICC was repositioned in the superior vena cava without further VT. He was discharged home the same day and underwent successful aortic valve replacement 2 months later. Position-dependent VT related to PICC requires careful history taking and PICC repositioning to make the diagnosis. X-ray in different patient positions during PICC placement can be considered to evaluate for ventricular migration.

catheter , ventricular tachycardia , cardiac arrhythmia , positional


Peripheral inserted central catheter (PICC) is widely used in clinical practice with overall excellent safety. Position-dependent ventricular tachycardia (VT) is a rare complication from PICC but has a good prognosis if treated in a timely manner. Special attention to clinical clues should be applied early on in the diagnostic evaluation. We report a typical presentation of position-dependent VT to reinforce awareness of this entity.

Case Report

A 51-year-old man was admitted to our hospital after several weeks of weight loss (approximately 40 pounds), dyspnea on exertion (New York Heart Association functional class II), and anemia. He had a history of aortic dissection status post repair and had undergone aortic valve replacement with a bioprosthetic valve 6 years prior. The patient was diagnosed with subacute bioprosthetic aortic valve endocarditis and aortic root abscess due to Lactococcus garvieae, and antibiotic therapy was started.

Figure 1. (A) Baseline electrocardiogram (ECG) of patient. (B) Chest X-ray after initial peripherally inserted central catheter (PICC) line placement. Course of PICC line to floor of right atrium can be seen (yellow arrowhead). (C) Telemetry strip of runs of mechanical induction of nonsustained ventricular tachycardia by PICC line during patient positioning. (D) Sinus rhythm ECG after withdrawal of PICC line to superior vena cava-right atrium junction.

The night before discharge, he developed multiple episodes of monomorphic nonsustained VT. The morning was uneventful with no new episodes of VT. The patient was asymptomatic for palpitations or chest pain, and vital signs and electrolytes were within normal limits. His electrocardiogram (ECG) on admission showed sinus rhythm and Q waves in the inferior leads (Figure 1 A). Upon further evaluation, it was found that a PICC had been inserted less than 24 hours earlier with the tip located in the upper right atrium (Figure 1 B). We asked the patient to show us how he sleeps, and he assumed a fetal position with abduction of the right arm and placement of the forearm under his head. He promptly developed palpitations and VT that resolved immediately when he sat up again (Figure 1 C). The PICC line was withdrawn 3 cm, and the patient had no further episodes of VT in his sleeping position. Post-repositioning ECG was unremarkable (Figure 1 D). Telemetry monitoring was continued for 8 additional hours with no evidence of VT. The patient was discharged the same day to complete outpatient parenteral antibiotic treatment with vancomycin and underwent aortic root abscess de-bridement and aortic valve replacement 1 month later.


First reported in the year 2000, position-dependent VT related to PICC is a well-described but potentially underreported phenomenon.3 In our patient, catheter-induced VT showed regular QRS and monomorphic morphology. The right inferior wall of the right ventricle was likely the location where the tip of the catheter was irritating the myocardium. This was supported by electrocardiographic monitoring showing a left bundle branch block (LBBB) morphology in V1, a positive QRS in lead augmented vector left, and a negative QRS in the inferior leads (Figure 1 B).

Use of PICC has expanded since it was first described in 1975, and approximately 3,000 catheters are inserted annually at our hospital.5 This increased use is likely because PICC has easy bedside placement, no risk of pneumothorax, minimal risk of bleeding, and long-term durability. Caudal migration of PICC catheter tip with arm abduction has been previously described, especially in catheters located in the right arm. The magnitude of this displacement is 21 mm with a range between 2 mm to 53 mm.6 Controversy exists over optimal positioning of the PICC catheter tip; some argue that placement in the SVC reduces catheter-induced arrhythmias, while positioning in the upper right atrium decreases the risk of displacement.2 From a practical standpoint, one possible approach would be to ask the patient to demonstrate their usual activities, including sleeping, to evaluate if the position triggers cardiac arrhythmias. X-ray in different patient positions during PICC placement may be considered to evaluate for ventricular migration.

In addition to PICC and central venous catheters, abandoned pacemaker leads have been reported to cause position-dependent VT.7

Approximately 2.5% of patients with endocarditis will develop acute coronary syndrome related to coronary artery compression that results from periannular complications or coronary arterial embolic events.8 Of those 2.5%, a small fraction will present with VT. In our patient, a resting normal ECG, the absence of coronary involvement on cardiac magnetic resonance imaging and coronary angiography, the reproducibility of the VT, and termination of the arrhythmia after changing position excluded the diagnosis of acute coronary syndrome.


Position-dependent VT related to PICC should be suspected in the appropriate clinical setting. Careful history taking, eliciting maneuvers, and resolution of the arrhythmia with change in position are important to make the diagnosis.

Conflict of Interest Disclosure

The authors have completed and submitted the Methodist DeBakey Cardiovascular Journal Conflict of Interest Statement and none were reported.

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