Methodist Journal



The Burgeoning Field of Cardio-Oncology

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Barry H. Trachtenberg Leads Issue on Cardio-Oncology

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Heart Failure in Relation to Anthracyclines and Other Chemotherapies

Heart Failure in Relation to Tumor-Targeted Therapies and Immunotherapies

The Role of Cardiovascular Imaging and Serum Biomarkers in Identifying Cardiotoxicity Related to Cancer Therapeutics

Prevention and Treatment of Chemotherapy-Induced Cardiotoxicity

Cardiovascular Toxicities of Radiation Therapy

Electrophysiologic Complications in Cancer Patients

Vascular Toxicity in Patients with Cancer: Is There a Recipe to Clarify Treatment?

Future Directions in Cardio-Oncology


A Rare Case of Pancreatitis-Induced Thrombosis of the Aorta and Superior Mesenteric Artery

Anomalous Origin of the Right Coronary Artery from the Left Main Coronary Artery in the Setting of Critical Bicuspid Aortic Valve Stenosis

Simultaneous Transfemoral Mitral and Tricuspid Valve in Ring Implantation: First Case Report with Edwards Sapien 3 Valve

Uneventful Follow-Up 2 Years after Endovascular Treatment of a High Flow Iatrogenic Aortocaval Fistula Causing Pulmonary Hypertension and Right Heart Failure


Do Not Pass Flow: Microvascular Obstruction on Cardiac Magnetic Resonance After Reinfarction Following Primary Percutaneous Coronary Intervention



Cardio-Oncology, Then and Now: An Interview with Barry Trachtenberg


Onconephrology: An Evolving Field


Herbal Nephropathy


Rolling the Dice on Red Yeast Rice


Letter to the Editor in Response to “Cardiac Autonomic Neuropathy in Diabetes Mellitus”

Vol 15, Issue 4 (2019)

Article Full Text


James K. Alexander, M.D.

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Article Citation:

James K. Alexander, M.D.. Methodist DeBakey Cardiovascular Journal: January 2013, Vol. 9, No. 1, pp. 63.

Dr. James K. Alexander was born December 25, 1920, in Evanston, Illinois, and died peacefully at his home in Houston, Texas, on March 29, 2009, at the exalted age of 88 years. To his friends and colleagues, he was addressed simply as “J.K.” He was educated at Amherst College with a degree in French and an eye initially on entering international law. He changed his mind in his senior year and decided on a medical career, subsequently taking all of his required pre-med science courses at Amherst. During this time, he became a champion squash player, excelled on the debate team, and learned to fly, thinking that if he were drafted, he would ”be above the fighting.”

Upon graduating from Amherst in 1942, he worked for a year before entering Harvard Medical School, where he graduated in 1947. He then fulfilled a 2-year commitment to the U.S. Army. Specialty training in internal medicine and cardiovascular disease followed, in part under the aegis of Drs. André F. Cournand and Dickinson W. Richards, who were later to become Noble laureates for their work as pioneers in cardiac catheterization. The fact that his parents were both teachers likely played a major role in his becoming a renowned teacher of the art and science of medicine. His mind was ever searching for new information or for correction of inaccuracies. I remember much about J.K., particularly his probing questions delivered to trainees or colleagues and especially to invited guest lecturers. His debate skills frequently came to the fore during exchanges at lectures.

After his training in cardiology, he moved to Houston in 1954 to work at Baylor College of Medicine, where he became a professor of medicine and eventually served as chairman of the sections of cardiology at Baylor, the VA Hospital, and Ben Taub Hospital. His private patients were seen at The Methodist Hospital, where he, along with Drs. Don W. Chapman and Ray Skaggs, was the first to perform right-heart catheterizations.


December 25, 1920 – March 29, 2009


He retired from Baylor in 2007 having earned many teaching and research awards as well as the deep respect of his peers and colleagues. Every cardiology trainee during his tenure became well acquainted with J.K. They were taught the importance of caring for each patient while searching for cures — the former more often obtainable than the latter. His epitaph, describing the aim of every physician, is a quote from the Memorial Statue of Dr. E.L. Trudeau that resonated with every student he encountered: “Cure occasionally, relieve often, console always.”

J.K.’s scientific interests lay in the function and pathophysiology of the heart, which he studied first through cardiac catheterization techniques learned from Drs. Cournand and Richardson and later using echocardiography, both of which he pioneered in the Texas Medical Center. He became the epitome of the classic clinical cardiologist, encompassing the skills of the basic scientist with the bedside manner of the fine clinician. He wrote extensively about the effect of obesity on the cardiovascular system. Studying the cardiovascular effects of high altitude led him on numerous occasions to Leadville, Colorado. There he was able to satisfy both his scientific curiosity and his passion for the outdoor life of camping, hiking, and especially fly fishing, which he managed to pursue over several continents. He scaled Mount Kilimanjaro in Tanzania on several occasions. On his last trip at age 75, he was connected to a Holter Monitor recording his heart rate and rhythm as he climbed. At an undisclosed altitude, he correctly determined it was time to go back down, as he had developed significant cardiac arrhythmias later proving to be ventricular in origin. He enjoyed music, as do many physicians, and served on the board of Houston Friends of Music. It is likely no surprise to learn that he was also an Eagle Scout.

The four qualities that I believe reside in a great physician — honesty, integrity, humility, and a sense of humor — all lived comfortably under the skin of J.K. He was a role model for many physicians and a friend to everyone. His easy smile, humor, and encyclopedic knowledge of cardiovascular medicine and life in general are still recalled with a quiet smile. His legacy as one of the building blocks of the Texas Medical Center, Baylor College of Medicine, and the Methodist DeBakey Heart & Vascular Center is firmly in place and recognized by all.


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